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ANNUAL OPEN grant program

Applications accepted January 20 – May 1, 2018

ARDF's Annual Open grant program was established to fund research projects that develop alternative methods to advance science and replace or reduce animal use. Proposals are welcome from any nonprofit educational or research institution worldwide, although there is a preference for U.S. applications in order to more quickly advance alternatives here.

Expert reviewers evaluate proposals based on scientific merit and feasibility, and the potential to reduce or replace the use of animals in the near future. Proposals are considered in fields of research, testing, or education. The maximum grant is $40,000, with an average 25% funding rate from 2012 to 2017.

Since 1993, ARDF has provided over $3.25 million in funds for projects in 29 states and 5 countries.

Scientific reviews are coordinated by the Institute for In Vitro Sciences, Gaithersburg, Maryland.


  • Maximum Award per Project: $40,000
  • Open Date: JANUARY 20, 2018
  • Deadline Date: MAY 1, 2018
  • Notification of Recipients: JULY 17, 2018


  • Non-profit, educational, and/or research institutions
  • May not use intact, non-human vertebrate or invertebrate animals
  • Research, testing, and education fields


  • Utilize in silico and in vitro methods with human cells or tissues
  • Use pathway-based approaches as exemplified by the 2007 National Academy of Sciences report, Toxicity Testing in the Twenty-first Century: A Vision and A Strategy
  • Are submitted by U.S. institutions